Researchers from the University of California, San Francisco (UCSF) looked at the length of telomeres, DNA sequences at the end of chromosomes that shorten as cells replicate and age.
The ageing and lifespan of normal, healthy cells are linked to the so-called telomerase shortening mechanism, which limits cells to a fixed number of divisions. During cell replication, the telomeres function by ensuring the cell's chromosomes do not fuse with each other or rearrange, which can lead to cancer. Elizabeth Blackburn, a telomere pioneer at the University of California San Francisco, likened telomeres to the ends of shoelaces, without which the lace would unravel.
[little hard to follow but makes sense if you read slowly]
With each replication the telomeres shorten, and when the telomeres are totally consumed, the cells are destroyed (apoptosis).
[main point is these buggers are indicators of the rate cells age]
Previous studies have also reported that telomeres are highly susceptible to oxidative stress. Some experts have noted that telomere length may be a marker of biological ageing.
“Among patients with stable coronary artery disease, there was an inverse relationship between baseline blood levels of marine omega-3 fatty acids and the rate of telomere shortening over 5 years,” wrote the researchers.
[Ta-da! Need I say more? That's big stuff. It means = Eat Fish!]
“These findings raise the possibility that omega-3 fatty acids may protect against cellular aging in patients with coronary heart disease,” they added.
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